Abstract
Human polymorphonuclear neutrophils (HPMNs) displayed attenuated hyphal damage associated with impaired O2- release following exposure to Rhizopus oryzae versus that with Aspergillus fumigatus. Exposure of HPMNs to R. oryzae hyphae resulted in upregulation in Toll-like receptor 2 mRNA and a robust proinflammatory gene expression with rapid (1-h) induction of NF-κB pathway-related genes.
Original language | English (US) |
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Pages (from-to) | 722-724 |
Number of pages | 3 |
Journal | Antimicrobial agents and chemotherapy |
Volume | 52 |
Issue number | 2 |
DOIs | |
State | Published - Feb 2008 |
Externally published | Yes |
ASJC Scopus subject areas
- Pharmacology
- Pharmacology (medical)
- Infectious Diseases