Zinc transport in pregnancy

Andrew W. Zimmerman; Barbara S. Dunham; David J. Nochimson; Bruce M. Kaplan; Jonathan M. Clive; Steven L. Kunkel

doi:10.1016/0002-9378(84)90029-2

Zinc transport in pregnancy

Andrew W. Zimmerman, Barbara S. Dunham, David J. Nochimson, Bruce M. Kaplan, Jonathan M. Clive, Steven L. Kunkel

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Abstract

Although the importance of zinc nutrition during pregnancy has been well recognized, there have been few studies of zinc transport in maternal or fetal sera. We examined total serum zinc levels as well as zinc associated with its major transport proteins, albumin and α₂-macroglobulin, prospectively in 46 women during gestation and in 27 of their infants at term. In five women who developed preeclampsia during the third trimester, the mean total serum zinc level at 6 to 14 weeks was decreased by 14% compared to control values (p <0.05). Fetomaternal differences between the zinc transport proteins support the concept that each may have a specific role(s) in zinc homeostasis which is regulated to a greater extent by metabolic factors than by dietary zinc intake alone.

Original language	English (US)
Pages (from-to)	523-529
Number of pages	7
Journal	American Journal of Obstetrics and Gynecology
Volume	149
Issue number	5
DOIs	https://doi.org/10.1016/0002-9378(84)90029-2
State	Published - Jul 1 1984
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)
Obstetrics and Gynecology

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10.1016/0002-9378(84)90029-2

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title = "Zinc transport in pregnancy",

abstract = "Although the importance of zinc nutrition during pregnancy has been well recognized, there have been few studies of zinc transport in maternal or fetal sera. We examined total serum zinc levels as well as zinc associated with its major transport proteins, albumin and α2-macroglobulin, prospectively in 46 women during gestation and in 27 of their infants at term. In five women who developed preeclampsia during the third trimester, the mean total serum zinc level at 6 to 14 weeks was decreased by 14% compared to control values (p <0.05). Fetomaternal differences between the zinc transport proteins support the concept that each may have a specific role(s) in zinc homeostasis which is regulated to a greater extent by metabolic factors than by dietary zinc intake alone.",

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AU - Zimmerman, Andrew W.

AU - Dunham, Barbara S.

AU - Nochimson, David J.

AU - Kaplan, Bruce M.

AU - Clive, Jonathan M.

AU - Kunkel, Steven L.

PY - 1984/7/1

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AB - Although the importance of zinc nutrition during pregnancy has been well recognized, there have been few studies of zinc transport in maternal or fetal sera. We examined total serum zinc levels as well as zinc associated with its major transport proteins, albumin and α2-macroglobulin, prospectively in 46 women during gestation and in 27 of their infants at term. In five women who developed preeclampsia during the third trimester, the mean total serum zinc level at 6 to 14 weeks was decreased by 14% compared to control values (p <0.05). Fetomaternal differences between the zinc transport proteins support the concept that each may have a specific role(s) in zinc homeostasis which is regulated to a greater extent by metabolic factors than by dietary zinc intake alone.

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Zinc transport in pregnancy

Abstract

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