Young Malaysian children with lower respiratory tract infection 's show low incidence of chlamydial infection

Y. F. Ngeow, A. F. Weil, N. S. Khairullah, M. Y. Mohd Yusof, L. Luam, C. Gaydos, T. C. Quinn

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Objective: The incidence of Chlamydia pneumoniae and Chlamydia trachomatis infection was studied among infants and young children admitted to hospital for the management of lower respiratory tract infections, over a 12 month period. Methodology: Respiratory secretions were examined for chlamydiae by cell culture, enzyme-linked immunosorbent assay and polymerase chain reaction-enzyme immunoassay. Sera were tested by micro- immunofluorescence for chlamydial IgG, IgM and IgA. Other bacterial and viral pathogens were also looked for by standard cultural and serological methods. Results: Of 87 patients aged 2 months-3 years, an aetiologic diagnosis was made in 41 (47.1%). C. pneumoniae and C. trachomatis were each detected in 1 (1.2%) of the patients. Among common bacterial pathogens, Haemophilus influenzae (13.8%) and Streptococcus pneumoniae (8.1%) were the most frequently identified. Respiratory viruses and elevated Mycoplasma pneumoniae antibodies were found in 10.3% and 9.1% of patients, respectively. Conclusion: Chlamydiae are infrequent causes of community-acquired acute lower respiratory tract infections in infants and very young children in Malaysia.

Original languageEnglish (US)
Pages (from-to)422-425
Number of pages4
JournalJournal of Paediatrics and Child Health
Issue number5
StatePublished - 1997


  • Children
  • Chlamydia
  • Respiratory infection

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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