XExploring concentration response in HIV pre-exposure prophylaxis to optimize clinical care and trial design

Craig W. Hendrix

doi:10.1016/j.cell.2013.09.030

XExploring concentration response in HIV pre-exposure prophylaxis to optimize clinical care and trial design

Craig W. Hendrix

School of Medicine

Research output: Contribution to journal › Review article › peer-review

45 Scopus citations

Abstract

HIV pre-exposure prophylaxis trials with antiretroviral drugs have been variably successful. Even trials demonstrating the best efficacy leave room for improvement. Pharmacological data illuminate several sources of outcome variability, especially the impact of poor adherence, which is critical to manage PrEP in the clinic and to develop the next generation of PrEP candidates.

Original language	English (US)
Pages (from-to)	515
Number of pages	1
Journal	Cell
Volume	155
Issue number	3
DOIs	https://doi.org/10.1016/j.cell.2013.09.030
State	Published - Oct 24 2013

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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10.1016/j.cell.2013.09.030

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abstract = "HIV pre-exposure prophylaxis trials with antiretroviral drugs have been variably successful. Even trials demonstrating the best efficacy leave room for improvement. Pharmacological data illuminate several sources of outcome variability, especially the impact of poor adherence, which is critical to manage PrEP in the clinic and to develop the next generation of PrEP candidates.",

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XExploring concentration response in HIV pre-exposure prophylaxis to optimize clinical care and trial design

Abstract

ASJC Scopus subject areas

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