Will a global subsidy of new antimalarials delay the emergence of resistance and save lives?

Ramanan Laxminarayan, Mead Over, David L. Smith

Research output: Contribution to journalReview articlepeer-review

41 Scopus citations

Abstract

Artemisinin-based combination treatments (ACTs) are seen as an important tool in the global effort to roll back malaria. With parasite resistance to chloroquine increasing rapidly in many parts of the world, there is greater recognition of the need for a globally coordinated strategy to ensure that artemisinins are not used as monotherapy, which has the potential to cut short their useful therapeutic life. We find that even a partial subsidy could delay the emergence of resistance and that a delay in implementing a subsidy for ACTs could facilitate the emergence of resistance and lower the economic value of ACTs.

Original languageEnglish (US)
Pages (from-to)325-336
Number of pages12
JournalHealth Affairs
Volume25
Issue number2
DOIs
StatePublished - Mar 2006
Externally publishedYes

ASJC Scopus subject areas

  • Health Policy

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