Whole-cell vaccines

Danijela Jelovac, Leisha A. Emens

Research output: Chapter in Book/Report/Conference proceedingChapter


Therapeutic cancer vaccines aim to generate tumor immunity through coordinated cell- and antibody-mediated responses that ultimately result in highly specific and potent T cells capable of destroying cancers. Cancer vaccines have unique advantages compared to most other cancer therapeutics, with a high degree of specificity for tumor cells relative to normal tissues, a highly favorable side-effect profile, and the potential for a long-lasting treatment effect due to immunologic memory.

Original languageEnglish (US)
Title of host publicationCancer Therapeutic Targets
PublisherSpringer New York
Number of pages14
ISBN (Electronic)9781441907172
ISBN (Print)9781441907165
StatePublished - Jan 1 2017


  • Chemotherapy
  • Combination immunotherapy
  • Immune response
  • Immunotherapy
  • Monoclonal antibody
  • Whole-cell vaccine

ASJC Scopus subject areas

  • General Medicine
  • General Biochemistry, Genetics and Molecular Biology
  • Pharmacology, Toxicology and Pharmaceutics(all)


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