When Hexokinase Gets that NAG-ing Feeling…

David O'Sullivan, Beth Kelly, Erika L. Pearce

Research output: Contribution to journalShort surveypeer-review

Abstract

Immune cell recognition of bacterial products usually occurs via specific pattern recognition receptors, but new research recently published in Cell by Wolf et al. (2016) demonstrates that the glycolytic enzyme hexokinase can act as an innate immune sensor by binding to bacterial derived N-acetylglucosamine (NAG).

Original languageEnglish (US)
Pages (from-to)198-200
Number of pages3
JournalCell Metabolism
Volume24
Issue number2
DOIs
StatePublished - Aug 9 2016
Externally publishedYes

ASJC Scopus subject areas

  • Physiology
  • Molecular Biology
  • Cell Biology

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