What happens when Trypanosoma brucei leaves Africa

Robert E. Jensen, Larry Simpson, Paul T Englund

Research output: Contribution to journalShort surveypeer-review

32 Scopus citations


Julius Lukeš and co-workers evaluated the evolutionary origin of Trypanosoma equiperdum and Trypanosoma evansi, parasites that cause horse and camel diseases. Although similar to T. brucei, the sleeping-sickness parasite, these trypanosomes do not cycle through the tsetse fly and have been able to spread beyond Africa. Transmission occurs sexually, or via blood-sucking flies or vampire bats. They concluded that these parasites, which resemble yeast petite mutants, are T. brucei sub-species, which have evolved recently through changes in mitochondrial DNA.

Original languageEnglish (US)
Pages (from-to)428-431
Number of pages4
JournalTrends in parasitology
Issue number10
StatePublished - Oct 2008

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases


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