TY - JOUR
T1 - Wallerian degeneration in peripheral nerve disease
AU - Griffin, J. W.
AU - George, E. B.
AU - Chaudhry, V.
PY - 1996
Y1 - 1996
N2 - Wallerian-like degeneration can be regarded as the final shared pathway of the most prevalent diseases of the peripheral nervous system, including many degenerative, metabolic, heritable, toxic, inflammatory and ischaemic disorders. The cellular responses that take place during Wallerian degeneration, including the elaboration of neurotrophins, are increasingly recognized to set the stage for the success or failure of subsequent regeneration, and manipulations of Wallerian degeneration are being investigated as a potential means of altering the outcome of nerve regeneration.
AB - Wallerian-like degeneration can be regarded as the final shared pathway of the most prevalent diseases of the peripheral nervous system, including many degenerative, metabolic, heritable, toxic, inflammatory and ischaemic disorders. The cellular responses that take place during Wallerian degeneration, including the elaboration of neurotrophins, are increasingly recognized to set the stage for the success or failure of subsequent regeneration, and manipulations of Wallerian degeneration are being investigated as a potential means of altering the outcome of nerve regeneration.
UR - http://www.scopus.com/inward/record.url?scp=0029960850&partnerID=8YFLogxK
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M3 - Review article
C2 - 8732200
AN - SCOPUS:0029960850
SN - 0961-0421
VL - 5
SP - 65
EP - 75
JO - Bailliere's Clinical Neurology
JF - Bailliere's Clinical Neurology
IS - 1
ER -