Wallerian degeneration in peripheral nerve disease.

V. Chaudhry; J. D. Glass; J. W. Griffin

doi:10.1016/s0733-8619(18)30200-7

Wallerian degeneration in peripheral nerve disease.

V. Chaudhry, J. D. Glass, J. W. Griffin

School of Medicine

Research output: Contribution to journal › Review article › peer-review

77 Scopus citations

Abstract

This article first reviews the different classes of nerve injury. The temporal evolution of electrophysiologic changes occurring during Wallerian degeneration in humans is then described, followed by a description of sequential structural changes and cellular responses that occur after nerve transection. The final section focuses on the basis for resurgent research interest in Wallerian degeneration and the different research approaches being taken to answer basic science and clinical questions.

Original language	English (US)
Pages (from-to)	613-627
Number of pages	15
Journal	Neurologic clinics
Volume	10
Issue number	3
DOIs	https://doi.org/10.1016/s0733-8619(18)30200-7
State	Published - Aug 1992

ASJC Scopus subject areas

Clinical Neurology

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10.1016/s0733-8619(18)30200-7

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title = "Wallerian degeneration in peripheral nerve disease.",

abstract = "This article first reviews the different classes of nerve injury. The temporal evolution of electrophysiologic changes occurring during Wallerian degeneration in humans is then described, followed by a description of sequential structural changes and cellular responses that occur after nerve transection. The final section focuses on the basis for resurgent research interest in Wallerian degeneration and the different research approaches being taken to answer basic science and clinical questions.",

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AB - This article first reviews the different classes of nerve injury. The temporal evolution of electrophysiologic changes occurring during Wallerian degeneration in humans is then described, followed by a description of sequential structural changes and cellular responses that occur after nerve transection. The final section focuses on the basis for resurgent research interest in Wallerian degeneration and the different research approaches being taken to answer basic science and clinical questions.

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Wallerian degeneration in peripheral nerve disease.

Abstract

ASJC Scopus subject areas

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