Wallerian degeneration in peripheral nerve disease.

V. Chaudhry, J. D. Glass, J. W. Griffin

Research output: Contribution to journalReview articlepeer-review

77 Scopus citations


This article first reviews the different classes of nerve injury. The temporal evolution of electrophysiologic changes occurring during Wallerian degeneration in humans is then described, followed by a description of sequential structural changes and cellular responses that occur after nerve transection. The final section focuses on the basis for resurgent research interest in Wallerian degeneration and the different research approaches being taken to answer basic science and clinical questions.

Original languageEnglish (US)
Pages (from-to)613-627
Number of pages15
JournalNeurologic clinics
Issue number3
StatePublished - Aug 1992

ASJC Scopus subject areas

  • Clinical Neurology


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