Voluntary movement dysfunction in Huntington's disease and tardive dyskinesia

A. S. David; D. V. Jeste; M. F. Folstein; S. E. Folstein

doi:10.1111/j.1600-0404.1987.tb07907.x

Voluntary movement dysfunction in Huntington's disease and tardive dyskinesia

A. S. David, D. V. Jeste, M. F. Folstein, S. E. Folstein

School of Medicine

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

ABSTRACT— Psychiatric patients with tardive dyskinesia (TD) may be difficult to distinguish from those with Huntington's Disease (HD), who frequently have psychiatric symptoms. This study compared 14 patients with HD with 21 patients (15 schizophrenics and 6 with affective disorder), matched for involuntary movements, using a quantitated neurological examination and other objective and semi‐objective tests. The HD group was significantly more impaired on measures of voluntary movement and saccadic eye movements. When the psychiatric group was subdivided, voluntary motor impairment was most marked in schizophrenics with both TD and parkinsonism. The implications of these findings are discussed.

Original language	English (US)
Pages (from-to)	130-139
Number of pages	10
Journal	Acta Neurologica Scandinavica
Volume	75
Issue number	2
DOIs	https://doi.org/10.1111/j.1600-0404.1987.tb07907.x
State	Published - Feb 1987

Keywords

Huntington's disease
quantitated neurological examination
schizophrenia
tardive dyskinesia
voluntary movement

ASJC Scopus subject areas

Neurology
Clinical Neurology

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10.1111/j.1600-0404.1987.tb07907.x

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AB - ABSTRACT— Psychiatric patients with tardive dyskinesia (TD) may be difficult to distinguish from those with Huntington's Disease (HD), who frequently have psychiatric symptoms. This study compared 14 patients with HD with 21 patients (15 schizophrenics and 6 with affective disorder), matched for involuntary movements, using a quantitated neurological examination and other objective and semi‐objective tests. The HD group was significantly more impaired on measures of voluntary movement and saccadic eye movements. When the psychiatric group was subdivided, voluntary motor impairment was most marked in schizophrenics with both TD and parkinsonism. The implications of these findings are discussed.

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Voluntary movement dysfunction in Huntington's disease and tardive dyskinesia

Abstract

Keywords

ASJC Scopus subject areas

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