VLSI multi-channel track-and-hold potentiostat

Roman Genov, Milutin Stanacevic, Mihir Naware, Gert Cauwenberghs, Nitish Thakor

Research output: Contribution to journalConference articlepeer-review

9 Scopus citations


Simultaneous mapping of neural activity facilitates understanding neurological phenomena and their underlying mechanisms. We present a track-and-hold potentiostat performing simultaneous acquisition of 16 independent channels of current ranging five orders of magnitude in dynamic range over four scales down to hundreds of picoamperes. Sampling rate ranges from DC to 200KHz. The system features programmable current gain control, configurable anti-aliasing log-domain filter, triggered current integration and provides differential output ready for asynchronous external analog-to-digital conversion over a compressed dynamic range. We present system description, circuit implementation and experimental results of real-time neurotransmitter concentration measurements from the 16-channel prototype fabricated in a 1.2 μm CMOS process.

Original languageEnglish (US)
Pages (from-to)117-128
Number of pages12
JournalProceedings of SPIE - The International Society for Optical Engineering
StatePublished - 2003
EventBioengineered and Bioinspired Systems - Maspalomas, Gran Canaria, Spain
Duration: May 19 2003May 21 2003


  • Analog VLSI
  • Biomedical instrumentation
  • Current-mode circuits
  • Dopamine sensor arrays
  • Log-domain signal processing
  • Potentiostat

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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