Vitamin A deficiency and anemia among micronesian children

Michelle Lloyd-Puryear; Jean H. Humphrey; Keith P. West; Kiosi Aniol; Frank Mahoney; Joan Mahoney; Deborah G. Keenum

doi:10.1016/S0271-5317(89)80061-2

Vitamin A deficiency and anemia among micronesian children

Michelle Lloyd-Puryear, Jean H. Humphrey, Keith P. West, Kiosi Aniol, Frank Mahoney, Joan Mahoney, Deborah G. Keenum

Bloomberg School of Public Health

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Vitamin A status was assessed by conjunctival impression cytology (CIC-A) and clinical signs in 60 systematically sampled 36-83 month old children attending a hospital outpatient department on Moen, Truk. Seventeen percent had xerophthalmia (12% with XN, 5% with XN+X1B). More than half (57%) were CIC-A abnormal reflecting mild subclinical vitamin A deficiency. CIC-A abnormal children were more anemic (by hematocrit, p<0.05) and were at greater risk of middle ear infection (OR=3.5, 95% CL: 0.8, 14.5). Vitamin A deficiency appears to be a previously unrecognized nutritional problem among Micronesian children, the causes for which are speculative at present.

Original language	English (US)
Pages (from-to)	1007-1016
Number of pages	10
Journal	Nutrition Research
Volume	9
Issue number	9
DOIs	https://doi.org/10.1016/S0271-5317(89)80061-2
State	Published - Sep 1989

Keywords

Micronesia
Truk
anemia
impression cytology
vitamin A deficiency

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Endocrinology
Nutrition and Dietetics

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10.1016/S0271-5317(89)80061-2

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title = "Vitamin A deficiency and anemia among micronesian children",

abstract = "Vitamin A status was assessed by conjunctival impression cytology (CIC-A) and clinical signs in 60 systematically sampled 36-83 month old children attending a hospital outpatient department on Moen, Truk. Seventeen percent had xerophthalmia (12% with XN, 5% with XN+X1B). More than half (57%) were CIC-A abnormal reflecting mild subclinical vitamin A deficiency. CIC-A abnormal children were more anemic (by hematocrit, p<0.05) and were at greater risk of middle ear infection (OR=3.5, 95% CL: 0.8, 14.5). Vitamin A deficiency appears to be a previously unrecognized nutritional problem among Micronesian children, the causes for which are speculative at present.",

keywords = "Micronesia, Truk, anemia, impression cytology, vitamin A deficiency",

author = "Michelle Lloyd-Puryear and Humphrey, {Jean H.} and West, {Keith P.} and Kiosi Aniol and Frank Mahoney and Joan Mahoney and Keenum, {Deborah G.}",

note = "Funding Information: This study was supported by the United States Public Health Service, Task Force Sight and Life, Basle, and Cooperative Agreement No. DAN-0045 between the International Center for Epidemiologic and Preventive Ophthalmology, the Johns Hopkins University, and the Office of Nutrition, Bureau for Science and Technology, United States Agency for International Development (USAID). The authors gratefully acknowledge the assistance of Lisa Mele, Mahmood Farazdaghi, and Drs. Alfred Sommer and David Morraga in carrying out this work.",

year = "1989",

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doi = "10.1016/S0271-5317(89)80061-2",

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AU - Lloyd-Puryear, Michelle

AU - Humphrey, Jean H.

AU - West, Keith P.

AU - Aniol, Kiosi

AU - Mahoney, Frank

AU - Mahoney, Joan

AU - Keenum, Deborah G.

N1 - Funding Information: This study was supported by the United States Public Health Service, Task Force Sight and Life, Basle, and Cooperative Agreement No. DAN-0045 between the International Center for Epidemiologic and Preventive Ophthalmology, the Johns Hopkins University, and the Office of Nutrition, Bureau for Science and Technology, United States Agency for International Development (USAID). The authors gratefully acknowledge the assistance of Lisa Mele, Mahmood Farazdaghi, and Drs. Alfred Sommer and David Morraga in carrying out this work.

PY - 1989/9

Y1 - 1989/9

N2 - Vitamin A status was assessed by conjunctival impression cytology (CIC-A) and clinical signs in 60 systematically sampled 36-83 month old children attending a hospital outpatient department on Moen, Truk. Seventeen percent had xerophthalmia (12% with XN, 5% with XN+X1B). More than half (57%) were CIC-A abnormal reflecting mild subclinical vitamin A deficiency. CIC-A abnormal children were more anemic (by hematocrit, p<0.05) and were at greater risk of middle ear infection (OR=3.5, 95% CL: 0.8, 14.5). Vitamin A deficiency appears to be a previously unrecognized nutritional problem among Micronesian children, the causes for which are speculative at present.

AB - Vitamin A status was assessed by conjunctival impression cytology (CIC-A) and clinical signs in 60 systematically sampled 36-83 month old children attending a hospital outpatient department on Moen, Truk. Seventeen percent had xerophthalmia (12% with XN, 5% with XN+X1B). More than half (57%) were CIC-A abnormal reflecting mild subclinical vitamin A deficiency. CIC-A abnormal children were more anemic (by hematocrit, p<0.05) and were at greater risk of middle ear infection (OR=3.5, 95% CL: 0.8, 14.5). Vitamin A deficiency appears to be a previously unrecognized nutritional problem among Micronesian children, the causes for which are speculative at present.

KW - Micronesia

KW - Truk

KW - anemia

KW - impression cytology

KW - vitamin A deficiency

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Vitamin A deficiency and anemia among micronesian children

Abstract

Keywords

ASJC Scopus subject areas

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