Visible-light optical coherence tomography for retinal oximetry

Ji Yi, Qing Wei, Wenzhong Liu, Vadim Backman, Hao F. Zhang

Research output: Contribution to journalArticlepeer-review

111 Scopus citations


We applied a visible-light spectroscopic optical coherence tomography (vis-OCT) for in vivo retinal oximetry. To extract hemoglobin oxygen saturation (sO2) in individual retinal vessels, we established a comprehensive analytical model to describe optical absorption, optical scattering, and blood cell packing factor in the whole blood and fit the acquired vis-OCT signals from the bottom of each imaged vessel. We found that averaged sO2 values in arterial and venous bloods were 95% and 72%, respectively.

Original languageEnglish (US)
Pages (from-to)1796-1798
Number of pages3
JournalOptics Letters
Issue number11
StatePublished - Jun 1 2013
Externally publishedYes

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics


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