Viruses and Congenital Malformations

Ralph A. Franciosi, Richard T. Johnson

Research output: Contribution to journalLetterpeer-review


To the Editor: I read with interest the fascinating article by Dr. Richard T. Johnson entitled “Effects of Viral Infection on the Developing Nervous System” published in the Journal for September 21. The observation on page 602 that lesions that fulfill the pathological criteria of primary agenesis or atresia can be caused by viral infection is fascinating and has been suspected in cases of congenital malformations of the central nervous system as well as biliary atresia. It would be of extreme interest to know if Dr. Johnson performed serologic studies to detect antibodies to the viral agent since such tests ….

Original languageEnglish (US)
Pages (from-to)1099-1100
Number of pages2
JournalNew England Journal of Medicine
Issue number21
StatePublished - Nov 23 1972

ASJC Scopus subject areas

  • General Medicine


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