Viral infections in interferon-γ receptor deficiency

S. E. Dorman, G. Uzel, J. Roesler, J. S. Bradley, J. Bastian, G. Billman, S. King, A. Filie, J. Schermerborn, S. M. Holland

Research output: Contribution to journalArticlepeer-review

137 Scopus citations


Interferon-γ receptor deficiency is a recently described immunodeficiency that is associated with onset of severe mycobacterial infections in childhood. We describe the occurrence of symptomatic and often severe vital infections in 4 patients with interferon-γ receptor deficiency and mycobacterial disease. The vital pathogens included herpes viruses, parainfluenza virus type 3, and respiratory syncytial virus. We conclude that patients with interferon-γ receptor deficiency and mycobacterial disease have increased susceptibility to some vital pathogens.

Original languageEnglish (US)
Pages (from-to)640-643
Number of pages4
JournalJournal of Pediatrics
Issue number5
StatePublished - 1999
Externally publishedYes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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