Viral antibodies in twins with multiple sclerosis

J. L. Woyciechowska, J. Dambrozia, P. Leinikki, C. Shekarchi, W. Wallen, J. Sever, H. McFarland, D. McFarlin

Research output: Contribution to journalArticlepeer-review

31 Scopus citations


Viral antibodies to measles, rubella, corona, vaccinia, and mumps viruses in serum and CSF (and to Epstein-Barr virus in serum only) were studied in 24 twin pairs, both discordant and concordant for clinical MS. In pairs, CSF antibody titers for rubella in MS monozygotic and dizygotic twins and for vaccinia in dizygotic twins were higher than for unaffected twins. Increased CSF titers among MS twins existed for measles, rubella, and vaccinia when pairing was ignored. Among MS twins, serum rubella and measles and CSF measles antibody titers, and CSF:serum ratios for measles virus, were higher in those who were DW, positive.

Original languageEnglish (US)
Pages (from-to)1176-1180
Number of pages5
Issue number8
StatePublished - 1985
Externally publishedYes

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology
  • Neuroscience(all)


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