Vincristine sulfate and radiation therapy in metastatic Wilms' tumor

Teresa J. Vietti, Margaret P. Sullivan, Mary E. Haggard, Thomas M. Holcomb, Daisilee H. Berry

Research output: Contribution to journalArticlepeer-review

44 Scopus citations


Complete regression of metastatic disease occurred in 16 of 22 (73%) children with Wilms' tumor treated with a combination regimen employing vincristine sulfate (Vcr) and radiation to the metastases. Ten of the 22 (45%) children are living and well for more than 2 years following treatment of their metastases. This survival figure might have been improved by more intensive radiation therapy, since 3 of the children failed to receive radiation therapy to all known metastatic sites. The response rate and quality and duration of response to Vcr plus radiation appear similar if not superior to that reported for actinomycin D plus radiation therapy in the treatment of metastatic Wilms'.

Original languageEnglish (US)
Pages (from-to)12-20
Number of pages9
Issue number1
StatePublished - Jan 1970
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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