Viable neurons with luxury perfusion in hydrocephalus

Ching Yee Oliver Wong, Mark G. Luciano, William J. MacIntyre, Richard C. Brunken, Joseph F. Hahn, Raymundo T. Go

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


A woman with hydrocephalus due to aqueductal stenosis had functional imaging of cerebral perfusion and metabolism to demonstrate the effects of endoscopic third ventriculostomy-a new form of internal surgical shunting. Technetium-99m-ECD SPECT and 18FFDG PET showed regional luxury perfusion at the left frontal region. Three months after a successful third ventriculostomy, a repeated imaging of cerebral perfusion and metabolism showed resolution of luxury perfusion and global improvement of both perfusion and metabolism. This concurred with postoperative clinical improvement. The paired imaging of cerebral perfusion and metabolism provides more information than just imaging perfusion or metabolism. Thus, the detection of perfusion and metabolism mismatch may open a new window of opportunity for surgical intervention.

Original languageEnglish (US)
Pages (from-to)1467-1470
Number of pages4
JournalJournal of Nuclear Medicine
Issue number9
StatePublished - Sep 1 1997
Externally publishedYes


  • Hydrocephalus
  • Perfusion and metabolism mismatch

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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