Venous thromboembolic disease: Clinical practice guidelines in oncology

Michael B. Streiff, Paula L. Bockenstedt, Spero R. Cataland, Carolyn Chesney, Charles Eby, John Fanikos, Patrick F. Fogarty, Shuwei Gao, Julio Garcia-Aguilar, Samuel Z. Goldhaber, Hani Hassoun, Paul Hendrie, Bjorn Holmstrom, Kimberly A. Jones, Nicole Kuderer, Jason T. Lee, Michael M. Millenson, Anne T. Neff, Thomas L. Ortel, Judy L. SmithGary C. Yee, Anaadriana Zakarija

Research output: Contribution to journalReview articlepeer-review

64 Scopus citations


Recognizing the increased risk of VTE in cancer patients is the first step in preventing the occurrence of VTE and promptly identifying VTE in these patients. The panel recommends VTE thromboprophylaxis for all hospitalized patients with cancer who do not have contraindications to this therapy, and also emphasizes that an increased level of clinical suspicion of VTE should be maintained for cancer patients. After hospital discharge, the panel recommends that cancer patients in a high-risk setting for VTE (e.g., patients who have undergone cancer surgery, those with multiple myeloma) continue to receive VTE prophylaxis, with the duration of anticoagulation determined by the clinical situation. Careful evaluation of cancer patients in whom VTE is suspected, and prompt treatment and follow-up for those diagnosed with VTE, is recommended after the cancer status of the patient is assessed and the risks and benefits of treatment are considered.

Original languageEnglish (US)
Pages (from-to)714-777
Number of pages64
JournalJNCCN Journal of the National Comprehensive Cancer Network
Issue number7
StatePublished - Jul 1 2011


  • Anticoagulation
  • Cancer
  • Deep venous thrombosis
  • Heparin
  • Low-molecular-weight heparin
  • NCCN clinical practice guidelines
  • NCCN guidelines
  • Prophylaxis
  • Pulmonary embolism
  • Superficial vein thrombosis
  • Treatment
  • Venous thromboembolism
  • Warfarin

ASJC Scopus subject areas

  • Oncology


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