Vasospasm and subsequent stroke from paraneoplastic syndrome in a pediatric patient with an intracranial mature teratoma: a case report

Amanda V. Jenson, Ali Yunus Rizvi, Rebecca A. Reynolds, Sara Hartnett-Wright, Thomas J. Gellar, Stacie Stapleton, Ignacio Gonzalez-Gomez, S. Hassan A. Akbari, Matthew D. Smyth

Research output: Contribution to journalArticlepeer-review

Abstract

Teratomas account for 18–20% of all intracranial germ cell tumors and mostly occur in the pineal region with only a few cases of pediatric sellar and suprasellar teratomas described in the literature. Here, we present a case of a child with an intracranial mature teratoma with pancreatic features causing vasospasm and subsequent stroke, found to be positive for CDKN2A—an independent variant associated with malignancy and small vessel disease leading to stroke.

Original languageEnglish (US)
Pages (from-to)2957-2960
Number of pages4
JournalChild's Nervous System
Volume40
Issue number9
DOIs
StatePublished - Sep 2024

Keywords

  • Intracranial teratoma
  • Paraneoplastic syndrome
  • Vasospasm

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

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