Vascular endothelium

M. O. Daugherty, G. F. Rich, R. A. Johns

Research output: Contribution to journalReview articlepeer-review


Our understanding of the vital function of the vascular endothelium in circulatory physiology is rapidly expanding. Endothelium-derived vasoactive substances influence vascular tone, growth, inflammation, and haemostasis. Endothelial dysfunction is implicated in the pathophysiology of cardiovascular diseases such as atherosclerosis, ischaemia-reperfusion injury, hypertension, and congestive heart failure. New pharmacological therapies are evolving from our understanding of the role of the endothelium.

Original languageEnglish (US)
Pages (from-to)88-94
Number of pages7
JournalCurrent Opinion in Anaesthesiology
Issue number1
StatePublished - Jan 1 1995
Externally publishedYes

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine


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