@article{c5b40556962147249b6a63ff2f245f44,
title = "Vascular anastomoses between the iris and persistent hyperplastic primary vitreous",
abstract = "Prominent radial iris blood vessels created small but definite pupillary notches in five children with persistent hyperplastic primary vitreous and persistence of the tunica vasculosa lentis. Detection of these abnormal iris vessels suggested the presence of persistent hyperplastic primary vitreous and related syndromes even when the diagnosis was obscured by the presence of an opaque lens. These vessels represented early developmental arrest and may have been associated with abnormal development of the macula and optic nerve. Surgical and amblyopia therapy, therefore, may not provide useful vision, and should be undertaken with caution.",
author = "Meisels, {Henry I.} and Goldberg, {Morton F.}",
note = "Funding Information: Case 1—A 23-month-old girl was first seen by us in July 1973 because of leukocoria in the right eye. Retinoblastoma was suspected. She was the product of an uncomplicated, full-term pregnancy. Examination with the patient under anesthesia revealed the corneal diameters to be R.E.: 11.5 mm horizontally by 10.5 mm vertically; L.E.: 11.0 mm horizontally by 11.5 mm vertically. Cycloplegic retinoscopy showed a refractive error in the right eye of a —14.00 diopter sphere +1.50 diopter cylinder x60 degrees; that of the left eye was a +0.75 diopter sphere. The anterior chamber of each eye was deep. The iris of the right eye had a small notch at 2:30 o'clock at the pupillary margin. A patent and abnormally prominent vessel extended from the stroma of the iris through the notch (Fig. 1) and around the equator of the lens to anastomose with the persistent posterior tunica vasculosa lentis (Figs. 2 and 3). A second tiny From the Department of Ophthalmology, University of Illinois Eye and Ear Infirmary, Chicago, Illinois. This study was supported in part by a grant from the Illinois Society for the Prevention of Blindness, Chicago; by an unrestricted grant from Research to Prevent Blindness, Inc., New York City; and grant Nos. EY4038 and EY1792 from the National Institutes of Health, Bethesda (Dr. Goldberg).",
year = "1979",
month = aug,
doi = "10.1016/0002-9394(79)90463-X",
language = "English (US)",
volume = "88",
pages = "179--181",
journal = "American journal of ophthalmology",
issn = "0002-9394",
publisher = "Elsevier Inc.",
number = "2",
}