Vascular abnormalities following radio- and chemotherapy of hepatic neoplasms: CT angiographic findings

Four patients (three with hepatocellular carcinoma and one with colorectal carcinoma metastatic to the liver) previously treated with chemotherapy or radiotherapy or both in an attempt to reduce tumor bulk prior to surgical resection were examined by CT angiography (CTA). Areas of abnormal enhancement and irregular vessels simulating tumor involvement proved to be free of neoplasm at surgery. Perfusion abnormalities and vascular irregularity on CTA following radiotherapy or chemotherapy should not be automatically considered as neoplastic. Tissue confirmation in such cases should be obtained to rule out treatment related hepatic parenchymal changes.