TY - JOUR
T1 - Vancomycin resistance, esp, and strain relatedness
T2 - A 1-year study of enterococcal bacteremia
AU - Harrington, S. M.
AU - Ross, T. L.
AU - Gebo, K. A.
AU - Merz, W. G.
PY - 2004/12
Y1 - 2004/12
N2 - The prevalence of esp, a gene associated with infection-derived and outbreak strains, in enterococcal blood isolates from 2002 was determined. Fifty-five of 137 (40.1%) Enterococcus faecalis isolates, 30 of 58 (51.7%) E. faecium isolates, 1 of 1 E. raffinosus isolate, 0 of 4 E. gallinarum isolates, and 0 of 1 E. casseliflavus isolate were positive. esp wasn't associated with vancomycin resistance (VR) or clinical service. VR E. faecium isolates were less genetically diverse than vancomycin-susceptible strains. A large cluster of VR isolates, belonging to esp-positive E. faecium, was revealed. These data support the hypothesis that esp and VR may contribute to dissemination of particular clones.
AB - The prevalence of esp, a gene associated with infection-derived and outbreak strains, in enterococcal blood isolates from 2002 was determined. Fifty-five of 137 (40.1%) Enterococcus faecalis isolates, 30 of 58 (51.7%) E. faecium isolates, 1 of 1 E. raffinosus isolate, 0 of 4 E. gallinarum isolates, and 0 of 1 E. casseliflavus isolate were positive. esp wasn't associated with vancomycin resistance (VR) or clinical service. VR E. faecium isolates were less genetically diverse than vancomycin-susceptible strains. A large cluster of VR isolates, belonging to esp-positive E. faecium, was revealed. These data support the hypothesis that esp and VR may contribute to dissemination of particular clones.
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U2 - 10.1128/JCM.42.12.5895-5898.2004
DO - 10.1128/JCM.42.12.5895-5898.2004
M3 - Article
C2 - 15583335
AN - SCOPUS:10844269435
SN - 0095-1137
VL - 42
SP - 5895
EP - 5898
JO - Journal of clinical microbiology
JF - Journal of clinical microbiology
IS - 12
ER -