Valve-sparing aortic root replacement in children: Intermediate-term results

Nishant Patel, George J. Arnaoutakis, Timothy J. George, Jeremiah G. Allen, Diane E. Alejo, Harry C. Dietz, Duke Cameron, Luca A. Vricella

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


Valve-sparing root replacement (VSRR) is an attractive option for aortic aneurysm in children with low-operative risk, but mid- and late-term results are not yet known. Between 1997 and 2009, 56 children (mean age 11.5 years) underwent VSRR at our institution. Twenty-six (46.4%) had Marfan syndrome and 24 (42.8%) had Loeys-Dietz syndrome. Mean preoperative max sinus diameter was 4.2 ± 0.8 cm (Z-score 7.7 ± 2.9). Five (8.9%) had >2± aortic insufficiency (AI). Two (3.6%) underwent David I reimplantation with a straight-tube, 12 (21.4%) had a Yacoub remodeling procedure, and 42 (75.0%) had reimplantation using a Valsalva-graft. There were one (1.8%) operative and three (5.4%) late deaths. One patient required reoperation for bleeding and one required late repair of a distal pseudoaneurysm. Mean follow-up was 5.2 years (range 0-12 years). No patients suffered thromboembolic events or had endocarditis. Of the 12 remodeling patients, four (33.3%) developed >2± AI and required aortic valve repair or replacement. No patient developed >2± AI after reimplantation. VSRR in children is a safe alternative to aortic root replacement with mechanical or biological prostheses. In this particular group of patients with connective tissue disorders and proclivity toward annular dilation and late AI, reimplantation is superior to remodeling.

Original languageEnglish (US)
Pages (from-to)415-419
Number of pages5
JournalInteractive cardiovascular and thoracic surgery
Issue number3
StatePublished - Mar 2011


  • Aortic aneurysm
  • Aortic root replacement
  • Pediatric

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine


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