Valproate for the treatment of medication-induced impulse-control disorders in three patients with Parkinson's disease

C. W. Hicks; M. M. Pandya; I. Itin; H. H. Fernandez

doi:10.1016/j.parkreldis.2011.03.003

Valproate for the treatment of medication-induced impulse-control disorders in three patients with Parkinson's disease

C. W. Hicks, M. M. Pandya, I. Itin, H. H. Fernandez

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

Abstract

Impulse-control disorders (ICDs) are becoming more commonly recognized in the Parkinson disease (PD) population. To date, there are no definitive methods of treating dopamine dysregulation syndromes in PD patients. We sought to uncover an effective treatment option for future study. We report a series of 3 PD patients with ICDs who were effectively treated with valproate. Based on these encouraging preliminary observations, future controlled clinical trials investigating the efficacy of valproate for ICDs in PD are recommended.

Original language	English (US)
Pages (from-to)	379-381
Number of pages	3
Journal	Parkinsonism and Related Disorders
Volume	17
Issue number	5
DOIs	https://doi.org/10.1016/j.parkreldis.2011.03.003
State	Published - Jun 2011
Externally published	Yes

Keywords

Dopamine dysregulation
Impulse-control disorder
Parkinson's disease
Valproate

ASJC Scopus subject areas

Neurology
Geriatrics and Gerontology
Clinical Neurology

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10.1016/j.parkreldis.2011.03.003

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AU - Itin, I.

AU - Fernandez, H. H.

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AB - Impulse-control disorders (ICDs) are becoming more commonly recognized in the Parkinson disease (PD) population. To date, there are no definitive methods of treating dopamine dysregulation syndromes in PD patients. We sought to uncover an effective treatment option for future study. We report a series of 3 PD patients with ICDs who were effectively treated with valproate. Based on these encouraging preliminary observations, future controlled clinical trials investigating the efficacy of valproate for ICDs in PD are recommended.

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KW - Valproate

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Valproate for the treatment of medication-induced impulse-control disorders in three patients with Parkinson's disease

Abstract

Keywords

ASJC Scopus subject areas

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