Validation of upper extremity post-thrombotic syndrome outcome measurement in children

Neil A. Goldenberg, Elizabeth Pounder, R. Knapp-Clevenger, Marilyn J. Manco-Johnson

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


Using the Manco-Johnson instrument in a derivation cohort of 107 children with or without a central venous catheter, upper extremity physical findings of post-thrombotic syndrome were absent, and the pain score was 0 in all but one child. Interrater reliability in an independent validation cohort (n = 38) of children with or without upper extremity deep venous thrombosis was 97%-100%.

Original languageEnglish (US)
Pages (from-to)852-855
Number of pages4
JournalJournal of Pediatrics
Issue number5
StatePublished - Nov 2010
Externally publishedYes


  • CVC
  • Central venous catheter
  • DVT
  • Deep venous thrombosis
  • LE
  • Lower extremity
  • PTS
  • Post-thrombotic syndrome
  • UE
  • Upper extremity
  • VTE
  • Venous thromboembolism

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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