Validation of simultaneous PET emission and transmission scans

C. J. Thompson, N. Ranger, A. C. Evans, A. Gjedde

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


A technique for performing simultaneous PET emission and transmission scans is validated in a fluoro-deoxyglucose study. A point source masked into a fan beam of annihilation photons orbits the patient section under study. Coincident events are sorted into two buffers, or rejected, based on the source's position. Both static and dynamic frames of independent and simultaneous studies are compared. The noise effective count rate is reduced to 62% of the value during normal studies. However, the increase in the coefficient of variation in cortical regions is <6%. The RMS difference between profile contours through many brain regions is ~40% higher comparing two simultaneous emission/transmission scans than when the same analysis is performed on independent emission scans. This difference appears to be due to the noise patterns arising from the use of different transmission scans.

Original languageEnglish (US)
Pages (from-to)154-160
Number of pages7
JournalJournal of Nuclear Medicine
Issue number1
StatePublished - 1991
Externally publishedYes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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