Validation of accelerometer placement to capture energy expenditure using doubly labeled water

Ryan J. Dougherty, Fangyu Liu, Lacey Etzkorn, Amal A. Wanigatunga, Peter J. Walter, Nicolas D. Knuth, Jennifer A. Schrack, Luigi Ferrucci

Research output: Contribution to journalArticlepeer-review


This study compared accelerometer-measured physical activity by body placement to daily total energy expenditure (TEE) and activity energy expenditure (AEE) measured using doubly labeled water (DLW). Forty-nine adult participants wore accelerom-eters placed on the nondominant wrist, dominant wrist, and chest while also undergoing DLW assessments. In adjusted mod-els, wrist-measured physical activity (p < 0.05), but not chest-measured physical activity (p > 0.05), was associated with TEE and AEE and explained a significant amount of variance that was not explained by age, sex, height, or body composition (R2 change = 0.04–0.08; all p < 0.05). Accelerometer placement location is an important consideration when using accelerometry to provide information about energy expenditure.

Original languageEnglish (US)
Pages (from-to)1045-1049
Number of pages5
JournalApplied Physiology, Nutrition and Metabolism
Issue number10
StatePublished - Oct 2022


  • ActiGraph
  • Actiheart
  • energy balance
  • energy regulation
  • metabolism

ASJC Scopus subject areas

  • Physiology (medical)
  • Nutrition and Dietetics
  • Physiology
  • Endocrinology, Diabetes and Metabolism


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