Using a deformable surface model to obtain a shape representation of the cortex

Christos Davatzikos

Research output: Contribution to journalArticlepeer-review

147 Scopus citations


This paper examines the problem of obtaining a mathematical representation of the outer cortex of the human brain, which is a key problem in several applications, including morphological analysis of the brain, and spatial normalization and registration of brain images. A parameterization of the outer cortex is first obtained using a dcformable surface algorithm which, motivated by the structure of the cortex, is constructed to find the central layer of thick surfaces. Based on this parameterization, a hierarchical representation of the outer cortical structure is proposed through its depth map and its curvature maps at various scales. Various experiments on magnetic resonance data are presented.

Original languageEnglish (US)
Pages (from-to)785-795
Number of pages11
JournalIEEE transactions on medical imaging
Issue number6
StatePublished - 1996
Externally publishedYes

ASJC Scopus subject areas

  • Software
  • Radiological and Ultrasound Technology
  • Computer Science Applications
  • Electrical and Electronic Engineering


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