USA: Contributions From the Institute for In Vitro Sciences and the Animal Protection Community

Rodger D. Curren, Erin H. Hill, Martin L. Stephens

Research output: Chapter in Book/Report/Conference proceedingChapter


In the United States, non-governmental organisations have played a major role over the last 30 or more years in moving in vitro toxicology from modest beginnings to routine use by many companies in their internal product stewardship and development programmes, as well as in many regulatory applications. The Institute for In Vitro Sciences is an example of a non-profit, science-based organisation, whose laboratories have consistently participated in major international and US validation programmes, resulting in the acceptance of many non-animal assays by regulatory agencies. Its Education and Outreach programmes have promoted and facilitated the use of these scientifically-validated assays throughout the world. US animal protection organisations have promoted this move away from animal testing in many ways, including mobilising consumers, lobbying legislators and regulators, and supporting Three Rs efforts financially.

Original languageEnglish (US)
Title of host publicationThe History of Alternative Test Methods in Toxicology
Number of pages9
ISBN (Electronic)9780128136980
ISBN (Print)9780128136973
StatePublished - Oct 22 2018


  • Alternatives
  • Animal protection
  • IIVS
  • In vitro
  • International regulations
  • Lobbying
  • Non-animal testing
  • Safety testing
  • Twenty-first century toxicology
  • Validation

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'USA: Contributions From the Institute for In Vitro Sciences and the Animal Protection Community'. Together they form a unique fingerprint.

Cite this