US Cohorts review: The HIV Outpatient Study (HOPS) and the Multicenter AIDS Cohort Study (MACS)

Frank J. Palella; Anne C. Moorman; John T. Brooks; John Phair; Lisa Jacobson; Roger Detels; Joseph Margolick; Charles Rinaldo

doi:10.1093/acprof:oso/9780199225859.003.0011

US Cohorts review: The HIV Outpatient Study (HOPS) and the Multicenter AIDS Cohort Study (MACS)

Frank J. Palella, Anne C. Moorman, John T. Brooks, John Phair, Lisa Jacobson, Roger Detels, Joseph Margolick, Charles Rinaldo

Bloomberg School of Public Health

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

This chapter presents an overview of HIV Outpatient Study (HOPS) and Multicenter AIDS Cohort Study (MACS). HOPS is a prospective observational cohort study that was initiated in 1993 by the US Centers for Disease Control and Prevention (CDC), and is currently expected to continue collecting and analyzing longitudinal data on HIV-infected outpatients until mid-2011. It is the longest-running and only remaining US governmentsponsored multi-site prospective cohort of a diverse spectrum of people living with HIV infection and receiving routine clinical care in the United States. MACS was funded in 1983 by the US National Institute of Allergy and Infectious Disease (NIAID), and recruitment of participants began in early 1984. The initial rationale for funding this epidemiological investigation was to collect specimens that could potentially be of use in identifying an infectious agent as the cause of AIDS and to delineate the natural history of pre-AIDS in men who have sex with men (MSM), the first epidemiologically identified group at high risk of developing the syndrome.

Original language	English (US)
Title of host publication	A Decade of HAART
Subtitle of host publication	The Development and Global Impact of Highly Active Antiretroviral Therapy
Publisher	Oxford University Press
ISBN (Electronic)	9780191723834
ISBN (Print)	9780199225859
DOIs	https://doi.org/10.1093/acprof:oso/9780199225859.003.0011
State	Published - Sep 1 2009

Keywords

Cohort studies
HAART
HIV infection
HIV/AIDS
Highly active antiretroviral therapy
Infectious agent
MSM

ASJC Scopus subject areas

General Medicine

Access to Document

10.1093/acprof:oso/9780199225859.003.0011

Cite this

Palella, F. J., Moorman, A. C., Brooks, J. T., Phair, J., Jacobson, L., Detels, R., Margolick, J., & Rinaldo, C. (2009). US Cohorts review: The HIV Outpatient Study (HOPS) and the Multicenter AIDS Cohort Study (MACS). In A Decade of HAART: The Development and Global Impact of Highly Active Antiretroviral Therapy Oxford University Press. https://doi.org/10.1093/acprof:oso/9780199225859.003.0011

Palella, FJ, Moorman, AC, Brooks, JT, Phair, J, Jacobson, L, Detels, R, Margolick, J & Rinaldo, C 2009, US Cohorts review: The HIV Outpatient Study (HOPS) and the Multicenter AIDS Cohort Study (MACS). in A Decade of HAART: The Development and Global Impact of Highly Active Antiretroviral Therapy. Oxford University Press. https://doi.org/10.1093/acprof:oso/9780199225859.003.0011

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US Cohorts review: The HIV Outpatient Study (HOPS) and the Multicenter AIDS Cohort Study (MACS)

Abstract

Keywords

ASJC Scopus subject areas

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