Urine screening for chlamydia trachomatis during pregnancy

Scott W. Roberts, Jeanne S. Sheffield, Don D. McIntire, James M. Alexander

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Objective: To compare the rates of Chlamydia trachomatis detection using urine and cervical secretions from pregnant women at our institution. Methods: A large cross-sectional sample of pregnant women (N=2,018) at 35-37 weeks of gestation were tested for C trachomatis with both endocervical and urine sampling using the Aptima Combo 2 Assay. Results: A prevalence of 4.3% and 4.1% were found for Chlamydia endocervical and urine samples, respectively. There was no difference between the two tests by McNemar's test (-0.02%, 0.32%; P=.083). There was excellent correlation between the tests found by the κ statistic (0.982 [0.961-1.000]). Conclusion: Urine sampling for C trachomatis is equivalent to endocervical sampling in pregnancy using the Aptima 2 Combo Assay.

Original languageEnglish (US)
Pages (from-to)883-885
Number of pages3
JournalObstetrics and gynecology
Issue number4
StatePublished - Apr 1 2011
Externally publishedYes

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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