Up to 8% of renal cancers are thought to have a hereditary component. Several hereditary renal cancer syndromes have been identified over the last few decades. It is important for the radiologist to be aware of findings associated with hereditary renal cancer syndromes to detect tumors early, enroll patients in appropriate surveillance programs, and improve outcomes for the patient and affected family members. This review discusses from a radiologist's perspective well-known hereditary renal cancer syndromes and emerging genetic mutations associated with renal cancer that are less well characterized, focusing on imaging features and known associations.
- Hereditary leiomyomatosis and renal cell cancer
- Hereditary renal cancer syndrome
- Renal cell carcinoma
- Tuberous sclerosis
- Von Hippel-Lindau disease
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging