Unrecognized Candida brain abscess in infancy: Two cases and a review of the literature

Two infants with presumed Candida species brain abscesses are presented. Six other infants with the same problem were found in a search of the literature, and some of the clinical and pathologic features of these patients are presented and discussed. All diagnoses were made post-mortem. There was frequent association with gastrointestinal pathology and subsequent surgery, and with antibiotic administration. Central nervous system signs and symptoms were not a prominent feature, and although most patients had disseminated candidiasis, one patient had an isolated macroscopic cerebral abscess.