Unique considerations in the assessment and management of traumatic brain injury in older adults

Bart Depreitere, Clemens Becker, Mario Ganau, Raquel C. Gardner, Alexander Younsi, Alfonso Lagares, Niklas Marklund, Victoria Metaxa, Susanne Muehlschlegel, Virginia F.J. Newcombe, Lara Prisco, Mathieu van der Jagt, Joukje van der Naalt

Research output: Contribution to journalReview articlepeer-review

Abstract

The age-specific incidence of traumatic brain injury in older adults is rising in high-income countries, mainly due to an increase in the incidence of falls. The severity of traumatic brain injury in older adults can be underestimated because of a delay in the development of mass effect and symptoms of intracranial haemorrhage. Management and rehabilitation in older adults must consider comorbidities and frailty, the treatment of pre-existing disorders, the reduced potential for recovery, the likelihood of cognitive decline, and the avoidance of future falls. Older age is associated with worse outcomes after traumatic brain injury, but premorbid health is an important predictor and good outcomes are achievable. Although prognostication is uncertain, unsubstantiated nihilism (eg, early withdrawal decisions from the assumption that old age necessarily leads to poor outcomes) should be avoided. The absence of management recommendations for older adults highlights the need for stronger evidence to enhance prognostication. In the meantime, decision making should be multidisciplinary, transparent, personalised, and inclusive of patients and relatives.

Original languageEnglish (US)
Pages (from-to)152-165
Number of pages14
JournalThe Lancet Neurology
Volume24
Issue number2
DOIs
StatePublished - Feb 2025

ASJC Scopus subject areas

  • Clinical Neurology

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