Abstract
Type II DNA topoisomerases are enzymes capable of passing one DNA duplex through another. A combination of structural and biochemical analyses is illuminating the mechanistic details of this transport reaction, revealing the sites of DNA and nucleotide binding and the existence of large-scale domain motions.
Original language | English (US) |
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Pages (from-to) | 26-32 |
Number of pages | 7 |
Journal | Current Opinion in Structural Biology |
Volume | 8 |
Issue number | 1 |
DOIs | |
State | Published - Feb 1998 |
Externally published | Yes |
ASJC Scopus subject areas
- Structural Biology
- Molecular Biology