Type II DNA topoisomerases

Research output: Contribution to journalArticlepeer-review

60 Scopus citations


Type II DNA topoisomerases are enzymes capable of passing one DNA duplex through another. A combination of structural and biochemical analyses is illuminating the mechanistic details of this transport reaction, revealing the sites of DNA and nucleotide binding and the existence of large-scale domain motions.

Original languageEnglish (US)
Pages (from-to)26-32
Number of pages7
JournalCurrent Opinion in Structural Biology
Issue number1
StatePublished - Feb 1998
Externally publishedYes

ASJC Scopus subject areas

  • Structural Biology
  • Molecular Biology


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