Type II DNA topoisomerases are enzymes capable of passing one DNA duplex through another. A combination of structural and biochemical analyses is illuminating the mechanistic details of this transport reaction, revealing the sites of DNA and nucleotide binding and the existence of large-scale domain motions.
|Original language||English (US)|
|Number of pages||7|
|Journal||Current Opinion in Structural Biology|
|State||Published - Feb 1998|
ASJC Scopus subject areas
- Structural Biology
- Molecular Biology