Two cases with progressive cystic leukoencephalopathy

Z. Yapici, G. Benbir, S. Saltik, L. He, G. K. Brown, R. W. Taylor, A. Dincer, S. Naidu, C. Yalcinkaya

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Leukoencephalopathies with cystic changes in the white matter on magnetic resonance imaging are aetiologically heterogeneous neurological disorders seen in children. A group of leukoencephalopathies characterised by white matter lesions progressing to multifocal cystic degeneration has been reported in various disorders, including mitochondrial enzyme deficiencies, leukodystrophies, and infectious processes. We report two patients with leukoencephalopathy showing progressive cystic changes on serial MRI, and magnetic resonance spectroscopy resembling progressive cavitating leukoencephalopathy.

Original languageEnglish (US)
Pages (from-to)47-51
Number of pages5
Issue number1
StatePublished - 2009


  • acute disseminated encephalomyelitis
  • episodic clinical deterioration
  • lactate in magnetic resonance spectroscopy
  • mitochondrial leukoencephalopathies
  • multiple sclerosis
  • progressive cystic leukoencephalopathy

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology


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