Abstract
We report the acute onset of aseptic sinusitis in 2 patients receiving the immune checkpoint inhibitors, ipilimumab and nivolumab, for treatment of metastatic melanoma. Ipilimumab, a monoclonal antibody targeting cytotoxic T-lymphocyte antigen-4, and nivolumab, targeting programmed cell death-1, have been associated with numerous immune-related adverse events. To the authors' knowledge, this is the first report of aseptic sinusitis as a consequence of immune checkpoint inhibition therapy.
Original language | English (US) |
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Pages (from-to) | 312-314 |
Number of pages | 3 |
Journal | Journal of Immunotherapy |
Volume | 40 |
Issue number | 8 |
DOIs | |
State | Published - 2017 |
Keywords
- immune checkpoint inhibitors
- immune-related adverse events
- sinusitis
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
- Pharmacology
- Cancer Research