Two alloantigens on human monocytes: A diallelic system?

Martine J. Jager; Frans H J Claas; Joe D'Amaro; Wink M. Baldwin; Jon J. van Rood

doi:10.1016/0198-8859(87)90116-9

Two alloantigens on human monocytes: A diallelic system?

Martine J. Jager, Frans H J Claas, Joe D'Amaro, Wink M. Baldwin, Jon J. van Rood

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

A positive monocyte crossmatch and therefore anti-monocyte antibodies are negative factors in bone marrow and renal transplantation. When the monocyte antigens themselves can be recognized, matching for the antigens involved here may become a possibility. In order to find useful anti-monocyte sera as typing reagents, human sera were screened aganst panel cells. Several monocyte specific sera were obtained. These sera recognized two monocyte antigens, HMA-1 and HMA-2. No similarity with any of the HLA antigens was observed. Every individual tested was positive for at least one of these two monocyte antigens, suggesting that HMA-1 and HMA-2 constitute a diallelic system.

Original language	English (US)
Pages (from-to)	215-224
Number of pages	10
Journal	Human Immunology
Volume	19
Issue number	3
DOIs	https://doi.org/10.1016/0198-8859(87)90116-9
State	Published - 1987
Externally published	Yes

ASJC Scopus subject areas

Immunology
Immunology and Allergy

Access to Document

10.1016/0198-8859(87)90116-9

Cite this

@article{99c69384b13d4d85b1e0e913a5f45004,

title = "Two alloantigens on human monocytes: A diallelic system?",

abstract = "A positive monocyte crossmatch and therefore anti-monocyte antibodies are negative factors in bone marrow and renal transplantation. When the monocyte antigens themselves can be recognized, matching for the antigens involved here may become a possibility. In order to find useful anti-monocyte sera as typing reagents, human sera were screened aganst panel cells. Several monocyte specific sera were obtained. These sera recognized two monocyte antigens, HMA-1 and HMA-2. No similarity with any of the HLA antigens was observed. Every individual tested was positive for at least one of these two monocyte antigens, suggesting that HMA-1 and HMA-2 constitute a diallelic system.",

author = "Jager, {Martine J.} and Claas, {Frans H J} and Joe D'Amaro and Baldwin, {Wink M.} and {van Rood}, {Jon J.}",

year = "1987",

doi = "10.1016/0198-8859(87)90116-9",

language = "English (US)",

volume = "19",

pages = "215--224",

journal = "Human Immunology",

issn = "0198-8859",

publisher = "Elsevier Inc.",

number = "3",

}

TY - JOUR

T1 - Two alloantigens on human monocytes

T2 - A diallelic system?

AU - Jager, Martine J.

AU - Claas, Frans H J

AU - D'Amaro, Joe

AU - Baldwin, Wink M.

AU - van Rood, Jon J.

PY - 1987

Y1 - 1987

N2 - A positive monocyte crossmatch and therefore anti-monocyte antibodies are negative factors in bone marrow and renal transplantation. When the monocyte antigens themselves can be recognized, matching for the antigens involved here may become a possibility. In order to find useful anti-monocyte sera as typing reagents, human sera were screened aganst panel cells. Several monocyte specific sera were obtained. These sera recognized two monocyte antigens, HMA-1 and HMA-2. No similarity with any of the HLA antigens was observed. Every individual tested was positive for at least one of these two monocyte antigens, suggesting that HMA-1 and HMA-2 constitute a diallelic system.

AB - A positive monocyte crossmatch and therefore anti-monocyte antibodies are negative factors in bone marrow and renal transplantation. When the monocyte antigens themselves can be recognized, matching for the antigens involved here may become a possibility. In order to find useful anti-monocyte sera as typing reagents, human sera were screened aganst panel cells. Several monocyte specific sera were obtained. These sera recognized two monocyte antigens, HMA-1 and HMA-2. No similarity with any of the HLA antigens was observed. Every individual tested was positive for at least one of these two monocyte antigens, suggesting that HMA-1 and HMA-2 constitute a diallelic system.

UR - http://www.scopus.com/inward/record.url?scp=0023275408&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023275408&partnerID=8YFLogxK

U2 - 10.1016/0198-8859(87)90116-9

DO - 10.1016/0198-8859(87)90116-9

M3 - Article

C2 - 3305437

AN - SCOPUS:0023275408

SN - 0198-8859

VL - 19

SP - 215

EP - 224

JO - Human Immunology

JF - Human Immunology

IS - 3

ER -

Two alloantigens on human monocytes: A diallelic system?

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this