Twin-to-twin transfusion syndrome (TTTS)

Ahmet Baschat, Ramen H. Chmait, Jan Deprest, Eduard Gratacós, Kurt Hecher, Efficia Kontopoulos, Ruben Quintero, Daniel W. Skupski, Dan V. Valsky, Yves Ville

Research output: Contribution to journalArticlepeer-review

59 Scopus citations


Twin-to-twin transfusion syndrome (TTTS) is a severe complication of monochorionic (MC) twin pregnancies, characterized by the development of unbalanced chronic blood transfer from one twin, defined as donor twin, to the other, defined as recipient, through placental anastomoses. If left untreated, TTTS is associated with very high perinatal mortality and morbidity rates, due to a combination of fetal and/or obstetric complications. The reported prevalence is 10-15% of all MC twins, or about 1 in 2000 pregnancies. This consensus document reviews available evidence and offers practical guidance to clinicians by providing recommendations on various aspects concerning diagnosis and management of TTTS.

Original languageEnglish (US)
Pages (from-to)107-112
Number of pages6
JournalJournal of Perinatal Medicine
Issue number2
StatePublished - Mar 1 2011
Externally publishedYes


  • Fetoscopy
  • MC twins
  • TTTS
  • laser treatment

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology


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