Twenty-One for 2021: The Most Influential Papers in Laryngology Since 2000

Marisa A. Ryan, Martin B. Brodsky, Joel H. Blumin, Jonathan M. Bock, Thomas L. Carroll, C. Gaelyn Garrett, Jerome R. Lechien, Julina Ongkasuwan, C. Blake Simpson, Lee M. Akst

Research output: Contribution to journalArticlepeer-review


Objectives/Hypothesis: To identify the most influential publications in laryngology since 2000. Study Design: Modified Delphi process. Methods: Samples of laryngologists drawn from editors of leading journals, organization officers, and thought leaders were invited to participate in a modified Delphi identification of influential laryngology papers. Influential was defined as follows: yielding meaningful practice changes, catalyzing further work as a foundation for an important topic, altering traditional views, or demonstrating durability over time. Quality and validity were not among the selection criteria. Each participant nominated 5 to 10 papers in Round 1. These nominations, augmented with papers from bibliometric analysis, were narrowed further in Round 2 as participants identified their top 20. The 40 papers with the most Round 2 votes were discussed by video conference and then subjected to Round 3 voting, with each participant again selecting their top 20 most influential papers. Final results were collated by the number of Round 3 votes. Results: Sixteen of 18 invited laryngologists participated overall (all 16 in Rounds 1 and 3; 14 in Round 2). Twenty-one papers were identified as most influential. One paper appeared on all 16 Round 3 lists; three papers with eight (50%) votes each were lasted to make the list. Eleven of these 21 focused on voice; three each related to cancer, airway, and swallowing; and one encompassed all of these clinical areas. Conclusions: This list of 21 influential laryngology papers serves to focus further research, provides perspective on recent advances within the field, and is an educational resource for trainees and practicing physicians. Level of Evidence: NA Laryngoscope, 132:406–412, 2022.

Original languageEnglish (US)
Pages (from-to)406-412
Number of pages7
Issue number2
StatePublished - Feb 2022

ASJC Scopus subject areas

  • Otorhinolaryngology


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