Tumor-induced osteomalacia (TIO): Atypical presentation

Waseem Khaliq, Praveen Cheripalli, Krishnarao Tangella

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Tumor-induced osteomalacia is a rare acquired condition characterized by phosphaturia, hypophosphatemia and osteomalacia. We report an unusual presentation in a 15-year-old healthy male with a two-week history of cough and chest pain. The chest radiograph showed right middle lobe opacity and chest CT revealed a mass in the extra pleural space. A biopsy showed chondro-myxoidstroma with osteoid formation. Diagnosis was confirmed with the above findings and hypophosphatemia. The patient's symptoms resolved after complete surgical excision of the mass. Tumor-induced osteomalacia, although a rare disorder, can be a diagnostic challenge, especially in patients presenting with atypical symptoms.

Original languageEnglish (US)
Pages (from-to)348-350
Number of pages3
JournalSouthern medical journal
Issue number5
StatePublished - May 1 2011


  • Tumor Induced Osteomalacia (TIO)
  • phosphaturic mesenchymal tumors (PMT)

ASJC Scopus subject areas

  • Medicine(all)


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