TY - JOUR
T1 - Tumor-induced osteomalacia (TIO)
T2 - Atypical presentation
AU - Khaliq, Waseem
AU - Cheripalli, Praveen
AU - Tangella, Krishnarao
PY - 2011/5
Y1 - 2011/5
N2 - Tumor-induced osteomalacia is a rare acquired condition characterized by phosphaturia, hypophosphatemia and osteomalacia. We report an unusual presentation in a 15-year-old healthy male with a two-week history of cough and chest pain. The chest radiograph showed right middle lobe opacity and chest CT revealed a mass in the extra pleural space. A biopsy showed chondro-myxoidstroma with osteoid formation. Diagnosis was confirmed with the above findings and hypophosphatemia. The patient's symptoms resolved after complete surgical excision of the mass. Tumor-induced osteomalacia, although a rare disorder, can be a diagnostic challenge, especially in patients presenting with atypical symptoms.
AB - Tumor-induced osteomalacia is a rare acquired condition characterized by phosphaturia, hypophosphatemia and osteomalacia. We report an unusual presentation in a 15-year-old healthy male with a two-week history of cough and chest pain. The chest radiograph showed right middle lobe opacity and chest CT revealed a mass in the extra pleural space. A biopsy showed chondro-myxoidstroma with osteoid formation. Diagnosis was confirmed with the above findings and hypophosphatemia. The patient's symptoms resolved after complete surgical excision of the mass. Tumor-induced osteomalacia, although a rare disorder, can be a diagnostic challenge, especially in patients presenting with atypical symptoms.
KW - Tumor Induced Osteomalacia (TIO)
KW - phosphaturic mesenchymal tumors (PMT)
UR - http://www.scopus.com/inward/record.url?scp=79955635523&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79955635523&partnerID=8YFLogxK
U2 - 10.1097/SMJ.0b013e31821427db
DO - 10.1097/SMJ.0b013e31821427db
M3 - Article
C2 - 21606715
AN - SCOPUS:79955635523
SN - 0038-4348
VL - 104
SP - 348
EP - 350
JO - Southern medical journal
JF - Southern medical journal
IS - 5
ER -