Tubular cell surface events during nephrolithiasis

Saeed R. Khan

Research output: Contribution to journalArticlepeer-review

37 Scopus citations


Kidney stone formation is the result of interactions among various constituents of the glomerular filtrate and between them and the renal tubular epithelial cells. Renal epithelial cells respond by producing modulators of nephrolithiasis which control crystal nucleation, growth, aggregation and retention within the kidneys. Exposure to excessive hyperoxaluria and calcium oxalate crystals injures the epithelial cells and promotes crystal retention.

Original languageEnglish (US)
Pages (from-to)240-247
Number of pages8
JournalCurrent Opinion in Urology
Issue number4
StatePublished - 1997
Externally publishedYes

ASJC Scopus subject areas

  • Urology


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