Trends and Updates on Cardiopulmonary Bypass Setup in Pediatric Cardiac Surgery

Ravi Medikonda, Chin Siang Ong, Rajeev Wadia, Dheeraj Goswami, Jamie Schwartz, Larry Wolff, Narutoshi Hibino, Luca Vricella, Daniel Nyhan, Viachaslau Barodka, Jochen Steppan

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


Perfusion strategies for cardiopulmonary bypass have direct consequences on pediatric cardiac surgery outcomes. However, inconsistent study results and a lack of uniform evidence-based guidelines for pediatric cardiopulmonary bypass management have led to considerable variability in perfusion practices among, and even within, institutions. Important aspects of cardiopulmonary bypass that can be optimized to improve clinical outcomes of pediatric patients undergoing cardiac surgery include extracorporeal circuit components, priming solutions, and additives. This review summarizes the current literature on circuit components and priming solution composition with an emphasis on crystalloid, colloid, and blood-based primes, as well as mannitol, bicarbonate, and calcium.

Original languageEnglish (US)
Pages (from-to)2804-2813
Number of pages10
JournalJournal of cardiothoracic and vascular anesthesia
Issue number10
StatePublished - Oct 2019


  • pediatric cardiac surgery
  • pediatric perfusion
  • perfusion

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Anesthesiology and Pain Medicine


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