Traumatic brain injuries: Predictive usefulness of CT

D. K. Kido, C. Cox, R. W. Hamill, B. M. Rothenberg, P. D. Woolf

Research output: Contribution to journalArticlepeer-review

35 Scopus citations


The computed tomographic (CT) scans from 72 patients with traumatic brain injury were reviewed to determine whether a specific type, location, or size of lesion correlated with changes in neurologic function (assessed with the Glasgow Coma Scale [GCS]), patient outcome (assessed with the Glasgow Outcome Scale [GOS]), or catecholamine levels. The lesions were classified as focal or diffuse. GOS changed as a function of lesion size (P = .00004) in the 48 patients with focal hemorrhages, regardless of whether the lesions were intra- or extraaxial, and in the 19 patients with normal CT scans. Patients with lesions larger than 4,100 mm3 had a twofold greater risk of a poor outcome than patients with smaller lesions (100% vs 50%). Patients with normal CT scans were significantly more likely to have mild neurological dysfunction or none than patients with abnormal CT scans (P = .03), but lesion location, skull fracture, and pineal shift were not significant predictors of GCS or GOS scores. A positive relationship existed between lesion size and both plasma norepinephrine and epinephrine levels (P < .02); a significant relationship existed between lesion size and GCS score (P = .02).

Original languageEnglish (US)
Pages (from-to)777-781
Number of pages5
Issue number3
StatePublished - 1992
Externally publishedYes


  • Brain, CT
  • Brain, hemorrhage
  • Brain, injuries
  • Trauma

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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