Transrectal prostate biopsy and fiducial marker placement in a standard 1.5T magnetic resonance imaging scanner

Robert C. Susil, Cynthia Ménard, Axel Krieger, Jonathan A. Coleman, Kevin Camphausen, Peter Choyke, Gabor Fichtinger, Louis L. Whitcomb, C. Norman Coleman, Ergin Atalar

Research output: Contribution to journalArticlepeer-review

73 Scopus citations


Purpose: We investigated the accuracy and feasibility of a system that provides transrectal needle access to the prostate concurrent with 1.5 Tesla MRI which previously has not been possible. Materials and Methods: In 5 patients with previously diagnosed prostate cancer, MRI guided intraprostatic placement of gold fiducial markers (4 procedures) and/or prostate biopsy (3 procedures) was performed using local anesthesia. Results: Mean procedure duration was 76 minutes and all patients tolerated the intervention well. Procedure related adverse events included self-limited hematuria and hematochezia following 3 of 8 procedures (all resolved in less than 1 week). Mean needle placement accuracy was 1.9 mm for the fiducial marker placement studies and 1.8 mm for the biopsy procedures. Mean fiducial marker placement accuracy was 4.8 mm and the mean fiducial marker placement accuracy transverse to the needle direction was 2.6 mm. All patients who underwent the procedure were able to complete their course of radiotherapy without delay or complication. Conclusions: While studies of clinical usefulness are warranted, transrectal 1.5 T MRI guided prostate biopsy and fiducial marker placement is feasible using this system, providing new opportunities for image guided diagnostic and therapeutic prostate interventions.

Original languageEnglish (US)
Pages (from-to)113-120
Number of pages8
JournalJournal of Urology
Issue number1
StatePublished - Jan 2006
Externally publishedYes


  • Biopsy
  • Interventional
  • Magnetic resonance imaging
  • Prostate
  • Prostatic neoplasms
  • Radiology

ASJC Scopus subject areas

  • Urology


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