Transforming growth factor β engages TACE and ErbB3 to activate phosphatidylinositol-3 kinase/Akt in ErbB2-overexpressing breast cancer and desensitizes cells to trastuzumab

Shizhen Emily Wang, Bin Xiang, Marta Guix, Maria Graciela Olivares, Joel Parker, Christine H. Chung, Atanasio Pandiella, Carlos L. Arteaga

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127 Scopus citations

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Biochemistry, Genetics and Molecular Biology

Immunology and Microbiology

Medicine and Dentistry

Pharmacology, Toxicology and Pharmaceutical Science