Transcription, splicing, and release: Are we there yet?

Ranjan Sen, Sebastian D. Fugmann

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


A systematic analysis of LPS-induced gene expression in macrophages by Bhatt et al. demonstrates that inflammatory responses are governed primarily at the level of transcription initiation. Unexpectedly, full-length nascent RNAs that contain introns appear to accumulate on chromatin, presumably to complete processing, prior to release of functional mRNA for export to the cytoplasm.

Original languageEnglish (US)
Pages (from-to)241-243
Number of pages3
Issue number2
StatePublished - Jul 20 2012
Externally publishedYes

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology


Dive into the research topics of 'Transcription, splicing, and release: Are we there yet?'. Together they form a unique fingerprint.

Cite this